As the United States ends its deadliest week since the beginning of the coronavirus pandemic, the first trucks full of COVID-19 vaccines have left a manufacturing facility Sunday morning, marking the start of the biggest vaccine distribution effort in US history.

Many people awoke this morning to images and videos of UPS semi trucks full of vaccines pulling out of a Kalamazoo, Mich., warehouse just two days after the Food and Drug Administration’s emergency approval of the Pfizer vaccine. The first batch of about 3 million vaccines is expected to reach high-risk health care workers and nursing homes.

The New York Times reports that after vaccines were packed in dry ice and loaded on to the trucks Sunday, “workers applauded as the first truck left the plant carrying a load of the vaccine.”

UPS and Fedex are working together to handle the staggered distribution of the vaccine getting it 636 locations across the country. The two shipping giants (who usually compete instead of working hand in hand) will monitor and track all vaccine shipments closely, and also alert all delivery drivers and pilots so they know they’re carrying a vaccine package. KEEP READING & WATCH VIDEO OF FIRST VACCINE DELIVERY